Biopharma Filters

  • One Commerce Center 1201 Orange ST. 600 Wilmington, DE 19899, USA
  • + (1) 603 795 0617
  • sales@biopharmafilters.com
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Chromatography Packings

Chromatography Packings

  • Description: Resins for protein purification & polishing.
  • Applications: mAb capture, enzyme purification, endotoxin removal.
  • Formats: Bulk resin, pre-packed columns.
  • Materials: Agarose, polymethacrylate, silica-based.
  • Types: Protein A, IEX, HIC, SEC.
  • Compliance: cGMP, USP Class VI, DMF available.
  • SOP (Summary):
    1. Pack columns under laminar flow.
    2. Clean with NaOH or citrate buffers.
  • Client Customizations: Particle size distribution, ligand density.
  • Process Notes: Regeneration protocols vary by ligand type.
  • Features: Protein A resins, ion exchange, and size exclusion beads

Description:

Chromatography resins are crucial for purification of proteins, antibodies, and peptides in downstream processing. Popular types include Protein A, ion exchange (IEX), hydrophobic interaction (HIC), and size exclusion chromatography (SEC) resins. These packings support high binding capacity, low leachables, and consistent performance. GMP-compliant chromatography media is widely used in capturing and polishing stages of mAb production. Available in bulk resin or pre-packed columns, they align with automated skid systems. Designed for scalability and chemical stability, these media are critical for biopharma workflows from clinical to commercial batches.